The Bulletín of Kanagawa Dental College

Vol. 36 No. 1       MARCH- 2008

ISSN: 0385-1443      UBIC: 65

ABSTRACT

The aim of this study is to establish procedures by which salivary biochemical markers can be used in community based screening for periodontal disease as an alternative to the Community Periodontal Idex (CPI). A total of 404 subjects who were undergoing an annual medical check-up and who had 20 or more remaining teeth were included in the analysis. The subjects consisted of 229 men and 175 women, and their mean age was 36.2+/-10.8. The salivary levels of lactate dehydrogenase (LDH), alkaline phosphates (ALP) and free hemoglobin (f-Hb) were measured and compared with the periodontal status derived from the CPI. For LDH, the sensitivity and specificity were 0.601 and 0.588, respectively, for CPI code 2 and 0.857 and 0.727 for CPI code 4. For f-Hb, a high specificity was obtained but not for sensitivity. For ALP, the dose response related cut-off points were obtained according to the CPI codes, and a relatively higher sensitivity (0.634) and specificity (0.714) were obtained for CPI code 4. Thus, it was determined that the salivary levels of LDH can be the predictor in screening for periodontal disease as an alternative to CPI. Key words: Periodontal disease / Periodontal pocket probing / CPI / Saliva.

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