JAPANESE JOURNAL OF ORAL & MAXILLOFACIAL SURGERY

Vol. 54 No. 2                     2008

ISSN: 0021-5163      UBIC: 151-J

ABSTRACT

A rare case of adenoid squamous cell carcinoma of the tongue is reported. A 61-year-old woman with cardiac sarcoidosis was an inpatient at our hospital. She was referred to us because of a white lesion on the tongue. An incisional biopsy was done, and the lesion was diagnosed to be a mucoepidermoid carcinoma. Partial glossectomy was performed with the patient under general anesthesia. Histologically, the surface layer of the neoplasm was squamous cell carcinoma. An adenoid squamous pattern was found in deep layers where pseudoglandular spaces containing exfoliated acantholytic tumor cells were observed. These pseudoglandulae were negative for alcian blue staining, but positive for anti-cytokeratin immunostaining. Consequently, the lesion was diagnosed to be an adenoid squamous cell carcinoma. As of 3 years and 6 months postoperatively, there has been no evidence of recurrence. key words: adenoid squamous cell carcinoma, tongue cancer, acantholysis, iodine staining.

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